marijuana painkillers

[Lunatic]

So the pharmaceutical industry fighting the marijuana tide finally realized they can't compete with nature. Of course this is all about money so they will use FDA to approve a pill derived from marijuana, so billions can be made, and the actual natural remedy, the plant itself will be banned. What happened to the claims marihuana is not good for medical purposes?

 

https://www.yahoo.com/news/high-hopes-ride-marijuana-painkillers-amid-opioid-crisis-142642440--finance.html

 

By Natalie Grover

(Reuters) - A handful of drugmakers are taking their first steps toward developing marijuana-based painkillers, alternatives to opioids that have led to widespread abuse and caused the U.S. health regulator to ask for a withdrawal of a popular drug this month.

The cannabis plant has been used for decades to manage pain and there are increasingly sophisticated marijuana products available across 29 U.S. states, as well as in the District of Columbia, where medical marijuana is legal.

There are no U.S. Food and Drug Administration (FDA)-approved painkillers derived from marijuana, but companies such as Axim Biotechnologies Inc, Nemus Bioscience Inc and Intec Pharma Ltd have drugs in various stages of development.

The companies are targeting the more than 100 million Americans who suffer from chronic pain, and are dependent on opioid painkillers such as Vicodin, or addicted to street opiates including heroin.

Opioid overdose, which claimed celebrities including Prince and Heath Ledger as victims, contributed to more than 33,000 deaths in 2015, according to the Centers for Disease Control and Prevention.

READ MORE: Yahoo News' Weed & The American Family series

Earlier this month, the FDA asked Endo International Plc to withdraw its Opana ER painkiller from the market, the first time the agency has called for the removal of an opioid painkiller for public health reasons. The FDA concluded that the drug's benefits no longer outweighed its risks.

FIGHTING THE EPIDEMIC

Multiple studies have shown that pro-medical marijuana states have reported fewer opiate deaths and there are no deaths related to marijuana overdose on record.(http://reut.rs/2r74Sbe)

But marijuana-derived drugs could take longer than usual to hit the market as the federal government considers marijuana a "schedule 1" substance - a dangerous drug with no medicinal value - making added approvals necessary. Any drug typically takes at least a decade from discovery to approval.

It could be worth the wait.

An FDA-approved marijuana-based painkiller would ensure consistent dosing and potency, and availability across the country, analysts and experts said.

"Doctors like to be able to write a prescription and know that whatever they wrote is pure and from a blinded, placebo-controlled trial," California-based Nemus's CEO Brian Murphy told Reuters.

Nemus is testing its product - a synthetic version of the non-psychoactive CBD compound found in cannabis - on rats with chronic pain and expects to report data later this year.

Rival Axim, whose North American headquarters is in New York, is conducting preclinical studies on a chewing gum containing synthetic CBD and THC, a psychoactive compound found in marijuana. The company expects to submit an FDA application to start a trial on opioid-dependent patients this year.

Leading the pack is Israel-based Intec, which recently announced the start of an early-stage study testing its painkiller made of natural CBD and THC extracts.

OTHER OPTIONS

Independent scientists are also looking to find natural, non-pharmaceutical alternatives to opioids, but many have said it is difficult to access government-approved marijuana to conduct research due to supply restrictions.

"It's taken me seven years to get the DEA license," said Dr Sue Sisley, who is planning to conduct an FDA-regulated study evaluating whether marijuana can help opioid-dependent patients.

There could soon be other alternatives as well. Pfizer Inc and Biogen Inc are among a clutch of drugmakers developing non-opioid painkillers that are in advanced clinical studies.

Still, opioid painkillers are here to stay and will continue to be widely prescribed, especially for patients with acute and post-surgical pain.

The Republican healthcare bill unveiled on Thursday has proposed a drastic cut to the Medicaid budget and could gut, what advocates say, is essential coverage for drug addiction treatment, potentially hampering the fight against opioid abuse.

 

[BHC]

I have a old friend who is fighting stage 4 cancer, a very rare cancer. Her father has the funds, and she must or family member must fly to California for cannabist oil, 3 month supply cost $8000. From what I see, it's working. In California one could be a NR and get the license to purchase and have it here in NJ, to get it you must go under a doctor's check up, but in a case like my friends, medical records are supplied and they go on the records. At first she got high, but after time she doesn't, but I'm convinced it's working, and modern western medicine isn't. The Federal government has admitted it works, yet they will not recognize it for medical treatment. NJ doesn't allow for the oil and I have no idea why, local states may or may not have it, but one must be a resident of that state. Taking it for medical reasons isn't smoking, it's in a capsule form, a roll on like deodorant, in foods, etc. Times have change, it must be recognized nationwide by the federal government for at least medical reasons

[1957Buck]

My point all along was make it Prescription Medication. you mentioned 3 month supply for  $8000.00 that is a Money Grab.  What  Prescription Costs that I have 2 that cost near $800. my copay is $40 for 3 month supply through Medco. ( Expresscripts  ) 

Mother nature my ass can be unreliable at least if the drug Companys dispense it. It has a better chance of being consistent.

 

Want it 2 ways leave the Pot stores to do their thing and Over Charge and on the other hand, make it available by Prescription so it will be available Reliably and Affordable. to many. 

.

[BHC]

she gets from a private person (firm) that is licenses to make these medical oils, in fact they take different forms of pot plants to make a oil for a certain cancer. $8000 is expensive but then you can't put a price on life. But once the FDA gets involved they will screw it all up

[BenedictGomez]

 

So the pharmaceutical industry fighting the marijuana tide finally realized they can't compete with nature. Of course this is all about money so they will use FDA to approve a pill derived from marijuana, so billions can be made, and the actual natural remedy, the plant itself will be banned. What happened to the claims marihuana is not good for medical purposes?

 

 

While there is a little, and I do stress little, truth to this, it is mostly liberal, left-wing propaganda.  

 

The big revenue painkillers from large pharma are in a different therapeutic class and work on different biological pathways than THC.   Not even remotely similar pharmacokinetically. 

 

If you Google this subject, you'll find 1,384,927 articles telling you it's all "Big Pharma" trying to stop the legalization of marijuana, again, it's 99% nonsensical leftist hippy BS.

[Lunatic]

I have a old friend who is fighting stage 4 cancer, a very rare cancer. Her father has the funds, and she must or family member must fly to California for cannabist oil, 3 month supply cost $8000. From what I see, it's working. In California one could be a NR and get the license to purchase and have it here in NJ, to get it you must go under a doctor's check up, but in a case like my friends, medical records are supplied and they go on the records. At first she got high, but after time she doesn't, but I'm convinced it's working, and modern western medicine isn't. The Federal government has admitted it works, yet they will not recognize it for medical treatment. NJ doesn't allow for the oil and I have no idea why, local states may or may not have it, but one must be a resident of that state. Taking it for medical reasons isn't smoking, it's in a capsule form, a roll on like deodorant, in foods, etc. Times have change, it must be recognized nationwide by the federal government for at least medical reasons

 

 

They don't allow it to protect revenues of pharmaceutical companies.

[Lunatic]

While there is a little, and I do stress little, truth to this, it is mostly liberal, left-wing propaganda.  

 

The big revenue painkillers from large pharma are in a different therapeutic class and work on different biological pathways than THC.   Not even remotely similar pharmacokinetically. 

 

If you Google this subject, you'll find 1,384,927 articles telling you it's all "Big Pharma" trying to stop the legalization of marijuana, again, it's 99% nonsensical leftist hippy BS.

 

 

Just look at the contributions from the pharms to our politicians. Its a huge lobby group protecting their interests.

[BHC]

Pharmacy firms are doing everything and anything to stop maijuana from becoming legal

[1957Buck]

Pharmacy firms are doing everything and anything to stop maijuana from becoming legal

 

Why wouldThey Fight it if they produced the Drugs made it would just add another Product to their Line.  Next to GM Linden where I worked was Merck A Foreign Manufacture. For years had conversations with a few workers there.  The reasoning was if they were to Produce any Medicines from it.  they would have to compete with the BILLION DOLLAR ILEGAL drug sales. But now that in some cases $8000 for 3 month supply from uncontrolled sources they are looking at it once again.  Conspire all you want If Merk put the same $8000 Med. on the Market for  $200  what is better or the Generic for $25. 

[BHC]

Cause they are in business for drugs, not the growing business. If they had and interest and I'm sure they looked into it already they would of started and or got lobbied to push it into law. Look at the success Colorado has had

[Haskell_Hunter]

It's your government that's preventing it from becoming a medicine.  Sessions is against legalization and wants to increase incarcerations.  Legal pot won't affect the pharmas.  I work for one and it's the least of their concerns.

 

If they are lobbing against pot, it means they are using the government to prevent it from becoming a medicine.  Public opinion is against them.

[hemlock]

..........

[Rusty]

They're all scumbags, doctors, pharmacists, drug companies, insurance companies . . .  

 

A few years back a doctor wrote me a prescription for niacin.  While the pharmacist was getting it I noticed niacin on the vitamin shelf, it was exactly the same as the prescription.   The bottle off the shelf cost only a few dollars.  When the pharmacist rang me up, his bottle was going to cost me $65 and insurance would pay the rest.  

 

I held up the bottle from the shelf and asked him the difference between his bottle and the one off the shelf, he said that they are exactly the same.   Except for the $200.  

[1957Buck]

They're all scumbags, doctors, pharmacists, drug companies, insurance companies . . .  

 

A few years back a doctor wrote me a prescription for niacin.  While the pharmacist was getting it I noticed niacin on the vitamin shelf, it was exactly the same as the prescription.   The bottle off the shelf cost only a few dollars.  When the pharmacist rang me up, his bottle was going to cost me $65 and insurance would pay the rest.  

 

I held up the bottle from the shelf and asked him the difference between his bottle and the one off the shelf, he said that they are exactly the same.   Except for the $200.  

 

Someone needs a New Doctor or was it an instant Care one.   All my Prescriptions for almost 30 years have been managed through a Managed Pharmacies Express Scripts at first then turned into Medco, Every new prescription is Revied By their Pharmacists for Generic - Over the Counter or Trier #1 they check for Pricing and interaction with any I am Taking.  If I have any questions 24-7 they are there.  Even if I go to CVS they do the same thing.  Medco even does a 1/4 review with a Registered Pharmacist to check on how they are working Generics are Aoutmaticly given unless script says prescribe as Written.    

As for all the scumbags, you better find a Medicine Man   

[B B]

I have a old friend who is fighting stage 4 cancer, a very rare cancer. Her father has the funds, and she must or family member must fly to California for cannabist oil, 3 month supply cost $8000. From what I see, it's working. In California one could be a NR and get the license to purchase and have it here in NJ, to get it you must go under a doctor's check up, but in a case like my friends, medical records are supplied and they go on the records. At first she got high, but after time she doesn't, but I'm convinced it's working, and modern western medicine isn't. The Federal government has admitted it works, yet they will not recognize it for medical treatment. NJ doesn't allow for the oil and I have no idea why, local states may or may not have it, but one must be a resident of that state. Taking it for medical reasons isn't smoking, it's in a capsule form, a roll on like deodorant, in foods, etc. Times have change, it must be recognized nationwide by the federal government for at least medical reasons

 

The oils are legal in NJ and currently available in one dispensary.  Most dispensary's do not have the ability to make it.  Check you PM's

Edited June 25, 2017 by B B